Experts discuss whether it's safe to rely on the allergy medicine. Benadryl is the leading brand for the antihistamine known as diphenhydramine. When you mix Benadryl with alcohol, these side effects are being of alcohol while under Benadryl medication in a supervised and safe. What will happen if I take 1, mg Benadryl, 2, mg Tylenol, 14, mg Zoloft , 35 mg Chlordiazepoxide, and mg Escitalopram, together with alcohol?. The combination of alcohol and Benadryl can slow down coordination and motor function, while also contributing to dizziness and sedation. Separately, both of these substances can cause dehydration. These are drugs that slow down your CNS. For example, cough syrups and laxatives visit web page have up to 10 percent alcohol content, and this can be a dangerous combination with Benadryl. FDA alerts for all medications. While it does not impact on the liver, Benadryl is a central nervous system CNS depressant, the same as alcohol. This warning is because of the risks of CNS depression from the drug. This is particularly common in children. Benadryl and alcohol have a sedating effect. For example, if you take anything else that causes drowsiness you are supposed to speak with your doctor about taking Benadryl. News U. Cameron, K. You already know that drinking alcohol and driving is dangerous. Dehydration can be a please click for source discomfort and, continue reading times, may make a benadrl worse than it already is. Always consult your healthcare provider to benasryl the information displayed on this page applies to your personal circumstances. Benadryl is a strong drug. Taking them together is dangerous because they can slow down your CNS too much. Drug Interaction Classification These classifications are only a guideline. Some types of medication, including cough syrup and laxatives, also contain alcohol. Learn More About Benadryl. Drug interactions are combinations of medication with other substances that may affect your health. Call us today. Benadryl is approved to treat allergy symptoms only. Mixing statins and alcohol might be risky if you have a history of heavy drinking. If you mix alcohol and Benadryl and you have a breathing issue such as Chronic obstructive pulmonary disease COPD or asthma, you may experience respiratory depression. Some of the side effects of diphenhydramine include drowsiness, dry mouth, headache or urination problems. When Benadryl and alcohol are taken together, both act on the CNS at the same time. Usually avoid combinations; use it only under special circumstances.